Xudong Xing

Xudong Xing

Professor at Beijing Institute of Genomics, Chinese Academy of Sciences (National Center for Bioinformation)

Xing Lab

Introduction

The Xudong Xing research team pioneers the innovative application of bioinformatics theories, methodological frameworks, and integrated technical systems to address frontier challenges of biomedicine. The team’s research centers on deciphering the hallmarks and sex differences underlying cancer progression and therapeutic outcomes, aiming to accelerate the translational development of novel cancer treatment strategies. Lab members pursue multidisciplinary research to uncover how complex molecular circuits are organized, regulated, and reshaped by genetic and environmental influences, cellular differentiation, and disease. In recent years, they have published 10 articles in top-tier journals, including Nature (2024), Cancer Cell (2025, 2024), Science Immunology (2023), Science Translational Medicine (2022), Science Advances (2021), and Nature Immunology (2020). These studies have received over 3,000 citations, with four papers designated as ESI Top 1% Highly Cited Papers. The team’s work has been highlighted in leading journals, including Cancer Cell (two articles), Nature Reviews Clinical Oncology, and Cancer Discovery.

Group leader

XING Xudong(邢旭东)

Biography

  • 2026.01-Present, Professor，Beijing Institute of Genomics, CAS（China National Center for Bioinformation）
  • 2024.10-2026.01, Principle Investigator，Beijing Institute of Genomics, CAS（China National Center for Bioinformation）
  • 2021.07-2024.09, BoYa Postdoctoral Researcher, Peking University
  • 2016.09-2021.07, Ph.D., Tsinghua University
  • 2011.09-2016.07, BS, Harbin Medical University

Introduction

Dr. Xing is currently serving as a Principal Investigator at China National Center for Bioinformation. He received his Ph.D. in Biology & Bioinformatics from Tsinghua University in 2021. Dr. Xing’s research encompasses diverse areas, including single-cell omics, cancer genomics, cancer neuroscience, and immuno-informatics. His primary research focuses on deciphering the hallmarks and sex differences underlying cancer progression and therapeutic outcomes, including:

  • Developing Artificial Intelligence Algorithms to Empower Early Cancer Detection and Intervention (Science Advances, 2021; Science Translational Medicine, 2022; Science Immunology, 2023).
  • Establishing Analytical Frameworks to Identify Hallmarks of Advanced Tumor Progression (Cancer Cell, 2024, 2025).
  • Building Data Models and Platforms to Decipher Sex Differences in Complex Diseases (Nature 2024; Nature Immunology 2020) Dr. Xing currently serves as Principal Investigator of several nationally research programs, including the National Key R&D Program of China, the Sponsored by Beijing Nova Program, and the National Natural Science Foundation of China.

Research Fields

  1. Biomedicine
  2. Single-cell Omics
  3. Bioinformatics

Patent

  1. A Method for Analyzing T-Cell Receptor Characteristics of T Lymphocytes Based on Single-Cell Multi-Omics Sequencing (ZL 2021 1 1213369.7)
  2. A Method for Analyzing B-Cell Receptor Characteristics of B Lymphocytes Based on Single-Cell Multi-Omics Sequencing (ZL 2021 1 1374293.6)

Group Members

  • SHI Xiaoyu，Postdoctoral fellow
  • TIAN Shuoran，Postdoctoral fellow
  • WANG Biying，Research Assistant
  • LIU Yukuan，PhD student
  • LI Rui，PhD student
  • ZHANG Zhipeng，PhD student
  • FU Hongyu，Msc student
  • LI Xize, Msc student
  • XU Xue, Msc student

Awards and Honors

Sponsored by Beijing Nova Program - 2025