Xudong Xing

Xudong Xing

Professor at Beijing Institute of Genomics, Chinese Academy of Sciences (National Center for Bioinformation)

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Single-cell landscape of immunological responses in patients with COVID-19

Published in Nature Immunology, 2020

An analysis of the single-cell landscape of immunological responses in patients with COVID-19, published in Nature Immunology.

Recommended citation: Ji-Yuan Zhang#, Xiang-Ming Wang#, **Xudong Xing#**, Zhe Xu#, ... , Fan Bai*, Fu-Sheng Wang*. (2020). "Single-cell landscape of immunological responses in patients with COVID-19." Nature Immunology 21, 1107-1118.

Decoding the multicellular ecosystem of lung adenocarcinoma manifested as pulmonary subsolid nodules by single-cell RNA sequencing

Published in Science Advances, 2021

Decoding the multicellular ecosystem of lung adenocarcinoma manifested as pulmonary subsolid nodules using scRNA-seq, published in Science Advances.

Recommended citation: **Xudong Xing#**, Fan Yang#, ... , Mantang Qiu*, Fan Bai*, Jun Wang*. (2021). "Decoding the multicellular ecosystem of lung adenocarcinoma manifested as pulmonary subsolid nodules by single-cell RNA sequencing." Science Advances 7, eabd9738.

Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis

Published in Science Translational Medicine, 2022

A study revealing aberrant lipid metabolism for early-stage diagnosis of lung cancer via scRNA-seq and lipidomics, published in Science Translational Medicine.

Recommended citation: Guangxi Wang#, Mantang Qiu#, **Xudong Xing#**, ... , Jun Wang*, Yuxin Yin*. (2022). "Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis." Science Translational Medicine 14, eabk2756.

Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8 + T cell metabolic fitness and function in tumors

Published in Science Immunology, 2023

Research on how mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell fitness in tumors, published in Science Immunology.

Recommended citation: Jie-Feng Yang#, **Xudong Xing#**, Li Luo#, Xin-Wei Zhou#, ... , Hui Han*, Fan Bai*, Song Gao*. (2023). "Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8 + T cell metabolic fitness and function in tumors." Science Immunology 8, abq2424.

Sex differences orchestrated by androgens at single-cell resolution

Published in Nature, 2024

This study explores sex differences orchestrated by androgens at single-cell resolution, published in Nature.

Recommended citation: Fei Li#, **Xudong Xing#**, Qiqi Jin#, Xiang-Ming Wang#, Pengfei Dai#, Ming Han#, ... , Chen Yu*, Luonan Chen*, Fan Bai*, Dong Gao*. (2024). "Sex differences orchestrated by androgens at single-cell resolution." Nature 629, 193-200.

Pan-cancer human brain metastases atlas at single-cell resolution

Published in Cancer Cell, 2025

Pan-cancer human brain metastases atlas at single-cell resolution. Cancer Cell (2025).

Recommended citation: **Xudong Xing#**, Jian Zhong#, Jana Biermann#, Hao Duan#, Xinyu Zhang#, Yu Shi#, ... , Yonggao Mou*, Benjamin Izar*, Nu Zhang*, Fan Bai*. (2025). "Pan-cancer human brain metastases atlas at single-cell resolution." Cancer Cell 43, 1-19.
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