CV

Education

September 2016 - July 2021, Tsinghua University, PhD
September 2011 - July 2016, Harbin Medical University, Bioinformatics, B.S.

Work experience

Fall 2024: Professor, Beijing Institute of Genomics, Chinese Academy of Sciences (National Center for Bioinformation)
Spring 2021: Postdoctoralscholar, Peking University

Publications

Pan-cancer human brain metastases atlas at single-cell resolution

**Xudong Xing#**, Jian Zhong#, Jana Biermann#, Hao Duan#, Xinyu Zhang#, Yu Shi#, ... , Yonggao Mou*, Benjamin Izar*, Nu Zhang*, Fan Bai*. (2025). "Pan-cancer human brain metastases atlas at single-cell resolution." Cancer Cell 43, 1-19.

Distinct roles of TREM2 in central nervous system cancers and peripheral cancers

Jian Zhong#, **Xudong Xing#**, Yixin Gao#, ... , Fan Bai*, Nu Zhang*. (2024). "Distinct roles of TREM2 in central nervous system cancers and peripheral cancers." Cancer Cell 42, 968-984.

Sex differences orchestrated by androgens at single-cell resolution

Fei Li#, **Xudong Xing#**, Qiqi Jin#, Xiang-Ming Wang#, Pengfei Dai#, Ming Han#, ... , Chen Yu*, Luonan Chen*, Fan Bai*, Dong Gao*. (2024). "Sex differences orchestrated by androgens at single-cell resolution." Nature 629, 193-200.

Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8 + T cell metabolic fitness and function in tumors

Jie-Feng Yang#, **Xudong Xing#**, Li Luo#, Xin-Wei Zhou#, ... , Hui Han*, Fan Bai*, Song Gao*. (2023). "Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8 + T cell metabolic fitness and function in tumors." Science Immunology 8, abq2424.

Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis

Guangxi Wang#, Mantang Qiu#, **Xudong Xing#**, ... , Jun Wang*, Yuxin Yin*. (2022). "Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis." Science Translational Medicine 14, eabk2756.

Decoding the multicellular ecosystem of lung adenocarcinoma manifested as pulmonary subsolid nodules by single-cell RNA sequencing

**Xudong Xing#**, Fan Yang#, ... , Mantang Qiu*, Fan Bai*, Jun Wang*. (2021). "Decoding the multicellular ecosystem of lung adenocarcinoma manifested as pulmonary subsolid nodules by single-cell RNA sequencing." Science Advances 7, eabd9738.

Single-cell landscape of immunological responses in patients with COVID-19

Ji-Yuan Zhang#, Xiang-Ming Wang#, **Xudong Xing#**, Zhe Xu#, ... , Fan Bai*, Fu-Sheng Wang*. (2020). "Single-cell landscape of immunological responses in patients with COVID-19." Nature Immunology 21, 1107-1118.

Xudong Xing

CV